Omaha 3 Ball successfully defended their Hoop It Up Pro Am championship by defeating NY Harlem 21-17 in the 2022 Hoop It Up National Championship October 15th in Mesa, Arizona. It was the second straight title for Omaha having won the 2021 title. Omaha will represent Hoop It Up on the FIBA World Tour. Omaha defeated Canadian champion Winnipeg as well as Team Infinite in the elimination rounds. Harlem knocked off top seeded Ariel and Wuxi Huishan to reach the finals.

Omaha went undefeated through the tournament after advancing to the elimination round after proceeding undefeated in pool play.